Understanding the Molecular Mechanisms of Complex Mutations

SDM: A server for predicting effects of mutations on protein stability

AP Pandurangan, B Ochoa-Montaño, DB Ascher, TL Blundell

2017-07-03

Here, we report a webserver for the improved SDM, used for predicting the effects of mutations on protein stability. As a pioneeri..

Combating mutations in genetic disease and drug resistance: understanding molecular mechanisms to guide drug design

ATS Albanaz, CHM Rodrigues, DEV Pires, DB Ascher

2017-06-03

Introduction: Mutations introduce diversity into genomes, leading to selective changes and driving evolution. These changes have c..